CS 190D/290D – Introduction to Bioinformatics - Fall 2006


Prerequisites: Undergraduate background in Computer Science

Lectures:

MW 1-3 pm, Phelps 1401

Instructor: Ambuj K. Singh

Office Hours: T 4-6 pm, Engr I, Rm. 3119, email: ambuj@cs.ucsb.edu

Enrollment Code: 70672

Reference material:

Primary

            Fundamental Concepts of Bioinformatics, D.E. Krane and M.L. Raymer, Pearson Education, 2003.

            Bioinformatics: Sequence and genome analysis, D. Mount, Cold Spring Harbor Laboratory Press, 2001.

            Algorithms on strings, trees, and sequences, D. Gusfield, Cambridge university press, 1997.

            Genes VII, B. Lewin, Oxford university press, 2000.

            Biochemistry (5th edition), Berg, Tymoczko, and Stryer, W. H. Freeman and company, 2001.

            Biological sequence analysis: probabilistic models of proteins and nucleic acids, Richard Durbin et al., Cambridge University Press, 1998.

Secondary

Computational Molecular Biology: An Algorithmic Approach, P. Pevzner, MIT press, 2000.

            Bioinformatics: the machine learning approach (2nd edition), P. Baldi and S. Brunak, MIT press, 2001.

            Principles of data mining, Hand, Mannila, and Smyth, MIT press, 2001.

            Post-genome informatics, M. Kanehisa, Oxford University Press, 2000.

            Current Topics in Computational Molecular Biology, eds. T. Jiang, Y. Xu, and M. Zhang, MIT press, 2002.

Course Material:

·        Course flyer

·        Lecture outline

·        Reading list

·        Homework assignments

·        Reading assignments

·        Class projects

·        Project milestone 1

External websites:

Human Genome Primer

Public Human Genome Project Publication In Nature 15 February 2001

Commercial Human Genome Sequence Published in Science 16 February 2001

NCBI Resources

SWISS-PROT

 

PDB

 

ISCB

 

Conferences and journals:

Bioinformatics

Journal of computational biology

Briefings in bioinformatics

            Nucleic Acids Research

Genome research

            RECOMB (available from ACM digital library)

            ISMB (available through Bioinformatics journal)

            PSB (available online)

Class email list