- (9/26, 9/28) Course overview, introduction to biology, biological databases, and bioinformatics
- (10/3, 10/5, 10/10) Sequence alignment (dynamic programming)
- (10/12, 10/17, 10/19, 10/24, 10/26) Evolution of sequences
- (10/31, 11/2) Database sequence search, Alignment statistics, Multiple alignment
- (11/7, 11/9) Multiple alignment, Hidden Markov Models
- (11/14, 11/16) Hidden Markov Models, Motif finding, EM
- (11/21, 11/23) EM, Gibbs sampling, Phylogenetic tree
- (11/28, 11/30) Phylogenetic tree, Course summary